What Are Nitrofurantoin And Bactrim
Nitrofurantoin is an antibiotic used to treat urinary tract infections caused by several types of bacteria including E. Coli, Enterobacter cystitis, Enterococcus, Klebsiella, and Staphylococcus aureus. Nitrofurantoin interferes with the production of bacterial proteins, DNA, and cell walls. Bacteria cannot survive without a cell wall or multiply without DNA. Three forms of nitrofurantoin are available: Furadantin, a microcrystalline form Macrodantin, a macrocrystalline and Macrobid, a sustained release form of macrocrystalline used twice daily. The macrocrystalline form is more slowly absorbed than the microcrystalline form and is useful for patients who cannot tolerate the microcrystalline form.
Bactrim is a combination of an antibacterial sulfonamide and a folic acid inhibitor. By combining both drugs, two important steps required in the production of bacterial proteins are interrupted, and the combination is more effective than either drug alone. Bactrim is used to treat bacterial infections including urinary tract infections, flares of chronic bronchitis due to bacteria, middle ear infections, for prevention of infections due to pneumococcus in organ transplant recipients, for the treatment or prevention of Pneumocystis cariniipneumonia, chancroid, and prevention of Toxoplasma encephalitis in patients with AIDS.
In other persons, lung injury may occur after approximately a month of treatment. Symptoms include:
- Difficulty breathing
How Can I Get Instant Relief From A Uti
Because most UTIs are bacterial, antibiotics for UTI treatment are the fastest way to get rid of a UTI and get relief.
Not just any antibiotic will cure your UTI. Some antibiotics are processed in a way that they never even reach the urinary tract. Other antibiotics may be equipped to fight off another type of bacteria, but not the one causing your UTI.
So, how do you know which antibiotic for UTI treatment is best for you?
The two most important questions you and your doctor need to consider are:
- What is the most likely bacteria causing the infection?
- What antibiotic is known to combat that bacterium?
With this, you doctor will prescribe you an antibiotic for UTI treatment and you should start feeling better in a few days.
Consume Apples And Apple Juice
Apples are also nutrient-dense. Their high acid content may help the kidneys to maintain acidity in the urine, possibly inhibiting further growth of bacteria. They also have anti-inflammatory properties, which may be beneficial in helping the kidneys to heal following the infection. Learn more about the many health benefits of apples.
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Dosage Forms And Strengths
Tell your doctor and pharmacist if:
Youre taking any prescription and nonprescription drugs or supplements, especially phenytoin
You have anemia or liver or kidney disease
You’re pregnant, planning to get pregnant, or breastfeeding. Call your doctor immediately if you become pregnant when taking trimethoprim .
Living With Urinary Tract Infections
If you have 3 or more urinary tract infections each year, your doctor may want you to begin a preventive antibiotic program. A small dose of an antibiotic taken every day helps to reduce the number of infections. If sexual intercourse seems to cause infections for you, your doctor many suggest taking the antibiotic after intercourse.
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When You Need Themand When You Dont
Antibiotics are medicines that can kill bacteria. Doctors often use antibiotics to treat urinary tract infections . The main symptoms of UTIs are:
- A burning feeling when you urinate.
- A strong urge to urinate often.
However, many older people get UTI treatment even though they do not have these symptoms. This can do more harm than good. Heres why:
Antibiotics usually dont help when there are no UTI symptoms.
Older people often have some bacteria in their urine. This does not mean they have a UTI. But doctors may find the bacteria in a routine test and give antibiotics anyway.
The antibiotic does not help these patients.
- It does not prevent UTIs.
- It does not help bladder control.
- It does not help memory problems or balance.
Most older people should not be tested or treated for a UTI unless they have UTI symptoms. And if you do have a UTI and get treated, you usually dont need another test to find out if you are cured. You should only get tested or treated if UTI symptoms come back.
Antibiotics have side effects.
Antibiotics can have side effects, such as fever, rash, diarrhea, nausea, vomiting, headache, tendon ruptures, and nerve damage.
Antibiotics can cause future problems.
Antibiotics can kill friendly germs in the body. This can lead to vaginal yeast infections. It can also lead to other infections, and severe diarrhea, hospitalization, and even death.
Antibiotics can be a waste of money.
When should older people take antibiotics for a UTI?
How Are Urinary Tract Infections Treated
You will need to treat a urinary tract infection. Antibiotics are medicines that kill bacteria and fight an infection. Antibiotics are typically used to treat urinary tract infections. Your healthcare provider will pick a drug that best treats the particular bacteria thats causing your infection. Some commonly used antibiotics can include:
Its very important that you follow your healthcare providers directions for taking the medicine. Dont stop taking the antibiotic because your symptoms go away and you start feeling better. If the infection is not treated completely with the full course of antibiotics, it can return.
If you have a history of frequent urinary tract infections, you may be given a prescription for antibiotics that you would take at the first onset of symptoms. Other patients may be given antibiotics to take every day, every other day, or after sexual intercourse to prevent the infection. Talk to your healthcare provider about the best treatment option for you if you have a history of frequent UTIs.
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What Are Some Risk Factors For Utis
However, people with penises can develop a UTI 3 in 25 men develop UTIs over their lifetime, according to the AUA . Other factors that make someone more prone to developing a complicated UTI include older age, being in the hospital , diabetes, kidney stones, pregnancy, and poor immune system health .
Certain behaviors increase your risk of developing a UTI. Using certain forms of birth control, such as spermicides or diaphragms, can increase your chances of a UTI. Poor hygiene, such as wiping from back to front , or other methods of moving germ-troublemakers to the entrance of your urinary tract, can increase your risk for a UTI.
Lastly, sexual intercourse can expose your urinary tract to UTI-causing germs. Other risk factors include menopause, previous UTIs, and urinary tract obstructions like kidney stones or an enlarged prostate .
Carefully Targeted Antibiotic Treatment For Urinary Tract Infections
So what do we do now? As a society and as individuals, we should reduce and carefully target antibiotic use. Both physicians and patients should be aware of the grave potential to lose effective antibiotics for all infections even simple UTIs. Its an opportunity that empowers individuals to have informed conversations with their doctors. Every time your doctor prescribes an antibiotic, ask: Do I need this? Why? Is there an antibiotic-free alternative? Talking about it might be enough to meaningfully reduce inappropriate antibiotic use.
If youre having UTI symptoms like burning with urination, more frequent urination, bloody or cloudy urine, low abdominal pain, or fever, you should see a medical provider to get tested. Youll have to urinate into a container and the medical office will test for products of bacterial metabolism. Make sure to tell your provider if youve had UTIs before, and what antibiotic you took. If you have a history of antibiotic-resistant infections, share that, too. There are alternatives to Cipro and Bactrim, but antibiotic choices are limited.
If antibiotic resistance continues to grow, more people will need intravenous treatment for UTIs we used to cure with simple oral antibiotic courses. Were also likely to see more complications, like kidney infections and sepsis, arising from ineffective treatment.
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Antibiotics That Shouldnt Be A First Choice For Uncomplicated Utis
Other antibiotics appear to be overused, and some physicians may misuse non-recommended antibiotics as first-line treatments. Ciprofloxacin is used in 35% of uncomplicated UTIs, while levofloxacin is used in 2%. These antibiotics can be important treatments in some cases of more complicated UTIs, but can have dangerous side effects.
The U.S. Food and Drug Administration warns that the use of these drugs should be restricted because of their potentially disabling side effects involving tendons, muscles, joints, nerves and the central nervous system. Additionally, in many parts of the country, bacteria commonly causing UTIs are becoming resistant to these antibiotics.
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What Does It Mean If You Have Recurring Utis
Recurrent urinary tract infections are widespread. One study found that 44% of women who experience acute uncomplicated cystitis will have a recurrence later that year, usually within three months from the initial episode. Most providers define recurrent UTIs as two or more infections in six months or three episodes or more over a year .
Recurrent UTIs usually do not indicate a failure of the first treatment, though the same strain of germs may have reinfected you. If your last infection happened recently, your healthcare provider might ask for a urine culture to see if the drug was active. A UTI is considered a relapse of the same infection if the recurrence happens within two weeks of a previous episode .
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Antibiotic Warnings And Treatment Concerns
The most commonly prescribed antibiotics for uncomplicated UTIs are similar in efficacy. But its important to note that ampicillin, amoxicillin, and sulfonamides are no longer the drugs of choice for combatting UTIs because of the emergence of antibiotic resistance. In addition, amoxicillin and clavulanate has been shown in previous research to be significantly less effective than others when it comes to treating urinary tract infections.
Also, as noted above, the FDA advises against using fluoroquinolones for uncomplicated UTIs. These medicines should only be considered if no other treatment options are available. In some cases, such as a complicated UTI or kidney infection, a healthcare provider may decide that a fluoroquinolone medicine is the best option, notes the American Academy of Family Physicians.
For pregnant women, some common antibiotics, such as fluoroquinolones and tetracyclines, should not be prescribed because of possible toxic effects on the fetus. But oral nitrofurantoin and cephalexin are considered good antibiotic choices for pregnant women with asymptomatic bacteriuria and acute cystitis, according to past research.
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Interactions Between Bactrim And Other Medications
Bactrim may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements that you are currently taking. The list below does not include all possible drug interactions with Bactrim . Please note that only the generic name of each medication is listed below.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
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Side Effects Of Bactrim For Dogs
The administration of pediatric bactrim in dogs can cause the appearance of:
- Hematopoietic alterations: these are alterations in the synthesis of the different cellular components of the blood.
- Alterations in the kidney and urinary tract: such as renal obstruction, crystalluria and hematuria .
To avoid kidney damage due to urolith formation, we must ensure the animal is kept well hydrated during treatment with bactrim. For this, it is essential that you always have fresh and clean water freely available.
How Does Bactrim Work
In 1973, Bactrim was approved by the FDA. Bactrim consists of two antibiotics: sulfamethoxazole and trimethoprim. Bacteria need folic acid to grow, and these two synthetic antibiotics impair the ability of bacteria to utilize folic acid. Sulfamethoxazole is a sulfa drug, which can interrupt dihydrofolic acid production. Trimethoprim, on the other hand, disrupts tetrahydrofolic acid production. These forms of folic acid are needed by human cells and bacteria for the production of proteins. Trimethoprim interrupts tetrahydrofolic acid production by disabling the enzyme that is responsible for the production of tetrahydrofolic acid from dihydrofolic acid.
The combination of sulfamethoxazole and trimethoprim inhibits bacterial protein production. Such antibiotic combination is also more effective than using each drug alone.
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What If I Dont Go To The Doctor
What happens when UTIs are left untreated? Contrary to popular belief, your immune system is often able to clear a UTI on its own. Studies have found that 25-42% of women are able to recover from an uncomplicated UTI without antibiotics.
But that means a majority of UTIs do not go away on their own. If left untreated, they can lead to continued discomfort and other more serious health issues, such as kidney damage or a severe infection. Therefore, treatment is recommended.
Physicians tailor care plans to each patient, and there is no sole treatment for everyone, says Stanford physician Kim Chiang, MD. During your visit, feel free to ask in-depth questions, particularly if a non-recommended antibiotic is prescribed.
This is the fifth post in the seriesUnderstanding UTIs. The goal of this seven-part series is to provide easy-to-understand, scientifically grounded information about UTIs. Patients referenced are composites, compiled from actual patient experiences.Data on medications used for UTIs were extracted from the National Disease and Therapeutic Index, a nationally representative physician survey produced by IQVIA.
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Antibiotics Used For Uncomplicated Utis
If you are a healthy individual whose urinary tract is anatomically and functionally normal and you have no known heightened UTI susceptibility youve got whats dubbed an uncomplicated UTI, according to guidelines published in August 2019 in the Journal of Urology. For these individuals, antibiotics are considered the first-line of treatment.
The type of antibiotics you are prescribed and for how long is contingent on the type of bacteria detected in your urine, your current health status, and whether your UTI is uncomplicated or complicated. Depending on which antibiotic your doctor prescribes, women may need a single dose or up to a five-day course. For men, antibiotics are usually given for a slightly longer period of time, notes UpToDate.
Typically, if you are diagnosed with an uncomplicated UTI, one of the following will be prescribed as first-line treatment:
The following antibiotics are considered second-line treatments for UTI. They are generally chosen because of resistance patterns or allergy considerations:
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How Do I Detox My Kidneys
There is no scientific evidence that kidney cleansing has any effect on kidney health. The best way to detoxify the kidneys is to not toxify them in the first place. Drink plenty of fluids, eat a nutritious diet, avoid processed foods, reduce salt intake, quit smoking, and avoid alcohol, caffeine, and unnecessary medications.
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Treatment For Utis Vs Kidney Infection Treatment
UTIs, including kidney infections, can be treated with a course of antibiotics. The type of antibiotic can depend on the type of bacteria thats causing your infection as well as how severe your infection is.
The doctor will often start you on an antibiotic that works against a wide variety of UTI-causing bacteria. If a urine culture is performed, the doctor may switch your antibiotic to one thats most effective at treating the specific bacterium thats causing your infection.
Simple UTIs can be treated with short 3- to 5-day courses of antibiotics. Treatment for kidney infections generally lasts 7 to 14 days, depending on which class of antibiotic is prescribed.
You may begin to feel better after only a few days on antibiotics. However, you should still make sure that you complete your entire treatment course as prescribed. If you do not take all of your antibiotics, the stronger bacteria may not be killed, causing your infection to persist and flare up again.
If youre pregnant, your doctor may also request a repeat urine sample following a kidney infection, even if your symptoms have resolved. This allows them to check to see whether your infection has completely cleared.
If there are still bacteria present in the sample, you may need another course of antibiotics. Persistence of bacteria can potentially harm an unborn baby.
People with severe kidney infections may need to be hospitalized. In this case, you may receive antibiotics and fluids intravenously.
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Regulatory Considerations And Drug Withdrawal And Milk Discard Times:
Sulfonamides are among the drugs for which extra-label use restrictions exist in lactating dairy cattle. Currently allowable drugs are sulfadimethoxine, sulfabromethazine, and sulfathoxypyridazine. In addition, sulfonamide residues, particularly in swine and poultry, continue to be a focus of detection. Because of adverse effects in people, including allergic reactions, attention must be made to withdrawal times. Regulatory requirements for withdrawal times for food animals and milk discard times vary among countries and may change. These must be followed carefully to prevent food residues and consequent public health implications. There are some prohibitions on use of sulfonamides in the USA, including use in dairy cattle. The times listed in Drug Withdrawal and Milk Discard Times of Sulfonamides Drug Withdrawal and Milk Discard Times of Sulfonamides Sulfonamides are the oldest and remain among the most widely used antibacterial agents in veterinary medicine, chiefly because of low cost and their relative efficacy in some common bacterial read more serve only as general guidelines.
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