Analysis At The Family Level
At the family level , Enterobacteriaceae was the most abundant species in groups N and B, with proportions of 48.52 and 69.58%, respectively. Enterobacteriaceae only accounted for 0.14% in group M. Staphylococcaceae was the most abundant species in group M, with a proportion of 82.61%, and Staphylococcaceae abundances were 0.35 and 0.77% in groups N and B, respectively.
Figure 9. The abundance of the family level.
The analysis of species differences is shown in Figure 10. Erwiniaceae and Aerococcaceae in group N were significantly increased . In group M, Enterobacteriaceae was significantly decreased, while Staphylococcaceae and Corynebacteriaceae were significantly increased . In group B, Enterococcaceae was significantly increased, and Micrococcaceae was significantly decreased .
Figure 10. Analysis of the differences at the level of the family level. *P 0.05 **P 0.01 ***P 0.001.
The Risks Of Medical Misinformation Vs The Benefits Of Reliable Sources
TikTok may be addictive, but their videos are no substitute for proper medical advice and can even prove outright dangerous. The spread of medical misinformation, myths, and fallacies is harmful for patients, says Christopher M. Zahn, MD, chief for clinical practice at ACOG. People seeking information about their health online should refer only to reliable, reputable sources.
“Just because information is online or on social media doesnt mean that it is true, or based on any reliable medical evidence. It is a sad reality that some people intentionally disseminate false information or simply decide to share unproven medical allegations without confirming the truth.”
As Tempting As It Is Trying To Self
For starters, you might not even have a yeast infection. There are studies that show we are actually really bad at self-diagnosis, noted Tanouye. Even people who have had yeast infections beforealthough theyre a little bit better at self-diagnosisits still not good.
This isnt your faultyeast infection symptoms are notoriously non-specific, so its not uncommon to mistake other conditions for a yeast infection. But if you try to treat with boric acidor even an over-the-counter antifungal creamand its not actually a yeast infection, youll most likely end up throwing off your vaginal microbiome even more. This imbalance and irritation can make you more vulnerable to other opportunistic infections, like STIs, explained Ghofrany. Not only that, but you may be delaying the diagnosis and treatment of something more serious by trying to troubleshoot at home.
I think it can be something that you ultimately self-treat, but only after an evaluation, said Ghofrany.
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Does Boric Acid Help With A Yeast Infection
- Boric acid is a naturally occurring compound with antifungal and antimicrobial properties.
- Boric acid suppositories are a safe and effective way to treat vaginal yeast infections.
- Within a few days of starting treatment, you may notice improvements in symptoms. Typically, the infection will clear within 1 to 2 weeks.
If you have recurrent or chronic yeast infections, boric acid may be a treatment worth investigating. Boric acid has been used to treat vaginal infections for over 100 years.
Not only is it antiviral and antifungal, but it also works to treat both Candida albicans and the more resistant Candida glabrata yeast strains.
Keep reading to learn more about this safe and affordable treatment method.
Boric acid is a water-soluble compound containing oxygen, boron, and hydrogen. Its a white substance that comes in powder or crystal form.
Researchers believe boric acid has antifungal and antibacterial properties.
2011 research review , researchers evaluated multiple studies revolving around boric acid as a treatment for recurrent vulvovaginal candidiasis.
They found 14 studies in total two randomized clinical trials, nine case series, and four case reports. Cure rates involving the use of boric acid varied between 40% and 100%, and none of the studies reported major differences in yeast infection recurrence rates.
What Does Boric Acid Do To Sperm
Sperm motility and duration were determined in sperm samples. In addition, fertility and hatching rate were examined. Our data indicated that addition of boric acid to activation media was increased the percentage and duration of motile sperm, fertility and hatching rate in endangered Anatolian trout (S.
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How To Use Boric Acid For Bv
If your healthcare provider gives you the OK, you can find OTC boric acid suppositories at your local pharmacy or drugstore. Most boric acid suppositories come in 600-milligram doses that you insert once a day for 1-2 weeks. For BV prevention, your doctor may suggest continuing treatment 2-3 times a week. Your healthcare provider may also suggest an entirely different treatment plan based on your individual BV situation.
Some folks also like to wear a pad or panty liner to help collect any discharge from the suppository. You will also want to avoid having sex while using boric acid suppositories and treating BV.¹
Make Your Own Capsules
We have heard that some women feel some dryness after taking boric acid. If you feel a bit dry after using the boric acid suppositories try making frozen coconut oil suppositories capsules. Keep them refrigerated and insert them at night, or a few hours after you have inserted the boric acid. Coconut oil kills off yeast infections which is another added bonus
How Long Does It Take For A Vaginal Suppository To Absorb
Answer: The length of time it takes for a vaginal suppository to dissolve varies on a number of factors, including your body temperature, the temperature of suppository prior to insertion, and the type of base. On average most suppositories will melt in 10-15 minutes, although it can take up to a half hours.
Before Taking This Medicine
You should not use boric acid if you are allergic to it, or if you have:
pain or tenderness in your pelvis or lower stomach
a weak immune system
blood vessel disorder or
if you are pregnant or breast-feeding.
It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.
Vaginal boric acid will not prevent pregnancy and should not be used as a form of birth control.
It is not known whether vaginal boric acid passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Vaginal boric acid is not approved for use by anyone younger than 12 years old.
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How To Use Boric Acid For Vaginal Infection
Follow the below steps to place the suppository into the vagina:
First, fill in the applicator.
Lie down on the back and bend your knees or stand by keeping one leg on the chair.
Release the capsule by pressing the plunger.
Softly remove the applicator.
Immune system disorders.
Using boric acid while you are pregnant is not safe for the fetus, as the ingredients in the boric acid suppository are toxic to the developing fetus.
If you are in your menstrual cycle and are using a boric acid suppository, then use sanitary napkins. While using boric acid, do not use tampons because they can absorb the medicine.
Detection Of Microflora Diversity
Skin samples frozen at 80°C were removed and treated with FastDNA SpinKitforSoil® to extract the total DNA of skin microorganisms. The library was prepared by DNA purity and concentration detection, and PCR amplification. The corresponding regions of bacterial 16srRNA and fungal ITS primers for high-throughput sequencing PCR amplification were shown in Table 1. Finally, the Miseq PE300/NovaSeqPE250 platform of Illumina Company was used for sequencing, reads-splicing and filtering, OTUs clustering, bioinformatics analysis, and data processing.
Table 1. PCR Sequencing regions and primer sequences.
What Is Boric Acid
Boric acid is a naturally occurring compound of sassolite found in volcanic waters and hot springs but is also readily found in most fruits and plants. Its used in the following industries:
- Industrial one of the main uses is in the manufacturing of monofilament fiberglass used to reinforce plastics in applications that range from boats, to industrial piping to computer circuit boards.
- Medical Apart from helping to cure bacterial vaginosis it is also used to treat minor cuts and burns and is commonly found in emergency eye rinses.
- Insecticidal It was first registered as an insecticidal back in 1948 and has since been used to control: cockroaches, termites, ants and many other insects.
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What Should I Watch For While Using This Medicine
Tell your doctor or health care professional if your symptoms do not start to get better within a few days.
It is better not to have sex until you have finished your treatment. This medicine may damage condoms or diaphragms and cause them not to work properly. It may also decrease the effect of vaginal spermicides. Do not rely on any of these methods to prevent sexually transmitted diseases or pregnancy while you are using this medicine.
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Boric Acid Safe For Chronic Yeast Infections
Is it safe to use boric acid suppositories to get rid of a chronic yeast infection?
Considering how common yeast infections are, youâd think the yeast that could be done is coming up with an easy, reliable way to get rid of them. Luckily, there are several potential options for treatment. The first step is to confirm that your symptoms are actually due to a vaginal yeast infection , which will likely involve a visit to a health care provider, such as a gynecologist, primary care provider, or sexual health clinic. After confirming that yeast is the true culprit, there are a variety of treatment options available to you, including over-the-counter remedies and prescription antifungal treatments. One such treatment option is boric acid suppositories, which may be especially helpful for yeast infections that are recurrent or resistant to other antifungal treatments. Recurrent infections are those that can be treated temporarily but come back . Boric acid is widely considered to be safe when used properly, although like any medication, there are some possible exceptions and potential side effects.
Benefits Of Boric Acid Suppositories
Boric acid may help improve vaginal health and has been shown to have anti-microbial and anti-fungal activity.
Research suggests that when used appropriately, boric acid suppositories can help reduce the risk of recurrent infections. At times, boric acid suppositories work more effectively than traditional medications, like some antifungals, which are used for treating yeast infections.
Boric acid may be recommended in some cases for:
- Yeast infections
- Bacterial vaginosis
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How To Use Boric Acid Suppositories
Typical treatment for a yeast infection includes leaving one suppository in overnight for seven days. For recurring infections, insert one suppository per evening for 14 days, then continue use for six months to a year twice a week.
How long you should use boric acid suppositories can vary and should always be discussed with your healthcare provider.
Does Boric Acid Treat Bacterial Vaginosis
BV can be frustrating if you have recurrent infections after antibiotic treatment. Studies show using boric acid suppositories with antibiotics as a complementary treatmentor as a preventive measurecan help treat some recurrent BV infections.³ But research on how effective boric acid is in treating BV is still limited. And using boric acid suppositories alone probably won’t cure your infection.
A 2020 review found that combining antibiotic treatment and 300- to 600-milligram boric acid suppositories twice a week helped treat recurrent BV and yeast infections. But using boric acid suppositories alone was ineffective. An older study from 2009 had similar findings, with a cure rate of 92% when women with BV took 600-milligram boric acid suppositories and antibiotics for 12 weeks.
The exact way boric acid works to help treat BV also isn’t fully understood. One theory is that it can help eliminate bacteria that cause the infection.
Just make sure you always consult your doctor before using a boric acid suppository if you think you have BV. Antibiotics in cream, gel, or pill form are still the most effective BV treatment since they kill the infection.²
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Quick Read Get Back In Balance
- Recurring or chronic yeast infections are when you have four or more infections per year.
- Boric acid can help treat yeast infections that are caused by an atypical strain of yeast or that are resistant to antifungal medication.
- When inserted vaginally, boric acid capsules disrupt fungi growth and help balance your vaginal flora.
Lets be honest, one yeast infection is bad enough. But burning, itching and cottage cheese discharge on repeat? Thats the stuff of nightmares.
Recurring yeast infections are when you have four or more documented infections per year, says Dr. Melanie Andersen, an OB-GYN who sees patients at UW Medicine Primary Care at South Lake Union and Womens Healthcare Center at UW Medical Center Roosevelt.
If youre one of the not-so-lucky folks logging multiple yeast infections per year, its likely youre looking for a treatment to put an end to the madness and boric acid might just be the answer to your fungal misfortune.
How Should I Use This Medicine
Talk to your pediatrician regarding the use of this medicine in children. This medicine is not approved for use in children.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
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Judgment Of Curative Effect
The curative effect was judged by the standard as described . A markedly effective refers to the original skin lesion healing after 7 days of treatment effective refers to the decrease of the original purulent exudate and improvement of skin lesion healing after 7 days of treatment. Ineffective means that the clinical symptoms are not significantly improved or even aggravated.
Is It Safe To Use Boric Acid Suppositories On Your Own For Vaginal Issues
If traditional treatments arent helping you kick recurring infections, definitely talk to your doc about trying out this alternative method before you go at it alone to make sure you do so safely.
You should *always* avoid oral use of boric acid because the substance is toxic when ingested. So, this also means you should avoid receiving oral sex after insertion for at least 24 to 48 hours, says Dr. Dweck. Additionally, if you find youre sensitive to boric acid or the capsule its contained in, then she recommends discontinuing use .
Potential side effects include redness, burning, and watery discharge, adds Dr. Gaither. Boric acid suppositories should also not be used during pregnancy or in the presence of open wounds.
Lastly, you should always obtain these capsules from a reputable pharmacy, Dr. Dweck says.
The bottom line: Boric acid suppositories may help prevent recurrent yeast or bacterial vaginosis infections after youve completed standard, doctor-recommended treatment.
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Boric Acid Vs Salicylic Acid:
Yeast infections are common in healthy adults. Researchers continue to search for treatments that have fewer side effects, better tolerability, and lower cost, as well as being highly effective.
A person can treat vaginal yeast infections with oral medications, usually antifungal. These require a prescription. Other medications are available without a prescription. Boric acid is a common alternative treatment that doctors recommend if first-line treatment hasnt worked or if the infection recurs. People with recurrent vaginal yeast infections may benefit from using boric acid capsules. A doctor can advise you on the best dose and how long to use the medicine.
What Are The Side Effects Of Boric Acid
Get emergency medical help if you have signs of an allergic reaction: hives difficult breathing swelling of your face, lips, tongue, or throat.
Stop using this medicine and call your doctor at once if you have:
- new or worsening symptoms
- symptoms that go away and come back.
Common side effects may include:
- watery vaginal discharge
- redness, mild burning or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Study Procedure And Data Collection
On day 0, a pregnancy test will be conducted and history will be collected by the clinician. During a pelvic examination, the clinician will ensure intact mucous membranes and anatomy, observe whether there is homogenous milky or creamy discharge , take swabs for chlamydia and gonorrhea, BV , candidiasis, and trichomonas, and perform a Whiff test using a provided standardized 10 % potassium hydroxide solution . Vaginal discharge will also be tested for pH . Where facilities permit clue cells will be examined, as the fourth Amsel criterion. On this day, the recruiting clinician will confirm participation, eligibility, and exclusion criteria using provided protocol forms and will collect the signed consent form and the demographic and medical history questionnaires provided.
The blinded treatment pack is allocated by the recruiting clinician in the randomization order to sequential participants on day 0. The participant package also contains: vaginal applicator pads non-lubricated non-latex condoms a diary to record daily use of the treatment information sheet outlining follow-up instructions and emergency contact numbers for the study members. Participants will self-administer the blinded treatment cream intravaginally each evening immediately prior to sleep for 10 days. The participants will be instructed to use a provided pad during day and night. Each participant will record daily compliance, side effects, and symptoms in the journal provided.