Common Antibiotics For Sinus Infections
Antibiotics may be prescribed when symptoms of a sinus infection warrant such treatment. Common antibiotics for sinus infection include:
- Levaquin : Although this drug is often prescribed as a first line of therapy for sinusitis, it has serious side effects and should only be used as a last resort.
Composition Of Doxycycline For Sinus Infection
The medicine is sold under various brand names such as Oracea, Doryx, Monodox, Periosta and Vibramycin. The main ingredient of Doxycycline 100 mg Tablet is doxycycline Hyclate which belongs to the tetracycline class of drugs. This is derived from oxytetracycline. It can work against a wide variety of drugs hence, it is a broad-spectrum antibiotic.
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What Is Sinusitis In Children
Sinusitis is an infection of the sinuses. These infections often happen after a cold or with allergies. There are 3 types of sinusitis:
Short-term . Symptoms of this type of infection last less than 12 weeks and get better with the correct treatment.
Long-term . These symptoms last longer than 12 weeks.
Recurrent. This means the infection comes back again and again. It means 3 or more episodes of acute sinusitis in a year.
The sinuses are air-filled spaces near the nose. They are lined with mucous membranes. There are 4 different sinuses:
Ethmoid sinus. Located around the bridge of the nose. This sinus is present at birth, and continues to grow.
Maxillary sinus. Located around the cheeks. This sinus is also present at birth, and continues to grow.
Frontal sinus. Located in the area of the forehead. This sinus does not develop until around age 7.
Sphenoid sinus. Located deep behind the nose. This sinus does not develop until the teen years.
When To Seek Medical Care
See a doctor if you have:
- Severe symptoms, such as severe headache or facial pain.
- Symptoms that get worse after initially improving.
- Symptoms lasting more than 10 days without improvement.
- Fever longer than 3-4 days.
You should also seek medical care if you have had multiple sinus infections in the past year.
This list is not all-inclusive. Please see a doctor for any symptom that is severe or concerning.
Other conditions can cause symptoms similar to a sinus infection, including:
- Seasonal allergies
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What Are The Most Common Antibiotics Used For Sinusitis
Amoxicillin remains the drug of choice for acute, uncomplicated bacterial sinusitis. Amoxicillin is most effective when given frequently enough to sustain adequate levels in the infected tissue. While often prescribed twice daily, it is even more effective if taken in 3 or 4 divided doses. Amoxicillin is typically prescribed for 7-10 days at a time. While it is critical to finish the entire 10 day course of antibiotics when treating strep throat, there is evidence that shorter courses of treatment may be sufficient for most cases of sinusitis. Amoxicillin is closely related to the parent compound penicillin and should not be prescribed in patients who are penicillin allergic.
Cephalosporins and Augmentin are considered broad-spectrum antibiotics because they have enhanced effectiveness against a wider range of bacteria, including those that are resistant to ordinary penicillin or amoxicillin. If the patient does not improve within the first week on amoxicillin, a change to Augmentin or to a cephalosporin such as Ceftin, Cefzil, Omnicef, or Suprax is reasonable. Although these drugs have a similar mechanism of action to penicillin, they generally can be taken in adequate doses once or twice daily. These medications should be used with extreme caution in patients with a history of penicillin allergy, as cross-reaction may occur.
Interactions Of Amoxicillin For Sinusitis
As the Amoxicillin 500 mg Tablet is allopathic medicine, it can easily react with other medicines that you are taking. The other medicines, when combined with Amoxicillin 500 mg tablet, can worsen the side effects of Amoxicillin 500 mg Tablet.
Not only the side effects but any underlying health issue can also aggravate if this medicine is taken without the doctors approval.
Medicines that can interfere with Amoxicillin 500 mg Tablet and can cause moderate or serious side effects are-
Know here:Best sinus medicines to take
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Nice Is Advising Healthcare Professionals To Tell Their Patients That A Sinus Infection Will Likely Clear
27 October 2017
The final guidance, developed with Public Health England, makes recommendations for treating acute sinusitis.
In most cases, people who have sinusitis will start to feel better within two-to-three weeks. The infection is usually viral, which means antibiotics should not be routinely prescribed, the guidance says.
Instead, NICE says healthcare professionals should advise their patients on how to manage their aches and pains with paracetamol.
They should also tell them that there is no evidence oral decongestants or steam inhalation will make any difference. And inform them that they should seek further medical advice if their symptoms get worse, or last for more than three weeks.
Dr Tessa Lewis, GP and chair of the managing common infections guidance committee, said: We know that most people with sinus infections will recover in a couple of weeks without needing any antibiotics, but that doesnt mean we should be sending them home without any information or advice.
Health professionals can help their patients cope with this infection and the sometimes unpleasant symptoms it can cause. They should tell them that theyll probably be feeling this way for a while, and that unless they are very unwell, the best thing to do is to take paracetamol and take it easy.
Professor Gillian Leng, deputy chief executive at NICE said:Antibiotic resistance is one of the greatest dangers to our health, which is why we must all work together to fight it.
Case & Commentary: Part 2
Shortly after starting her second course of antibiotics, the patient began feeling unwell. A few days later, she was found down in her home by her daughter. The patient was brought to the emergency department for evaluation. Her work up revealed profound anemia due to brisk autoimmune hemolysis. This was thought to be due to the amoxicillin-clavulanate she had received. She was started on high-dose immunosuppressive therapy with steroids.
The chief population-level effect of antibiotic overuse is the widespread and growing problem of antimicrobial resistance . AMR is a worsening problem among many bacteria, including Staphylococcus aureus, Streptococcus pneumoniae, and Escherichia coliorganisms that cause common clinical syndromes such as cellulitis, community-acquired pneumonia, and urinary tract infection. Once confined to hospitals, these drug-resistant pathogens are becoming increasingly prevalent in the community setting, and some data indicate that prior treatment with antibiotics may increase an individual patient’s likelihood of contracting an infection with a drug-resistant bacteria. AMR exerts significant societal costs, as infections with drug-resistant bacteria are associated with increased morbidity, mortality, and health care expenditures.
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What Are The Best Antibiotics For Sinus Infection Do Doctors Prescribe For You
There are many antibiotics that your doctor or physician may prescribe to help treat your sinus infection. Some of these may even be familiar to you.
These antibiotics are effective in treating sinus infection, however, these drugs do carry side effects. You should only be taken according to what your doctor or physician has prescribed. Always follow their instructions to achieve the best results.
Can Sinus Infections Or Sinusitis Be Prevented
Currently, there are no vaccines designed specifically against infectious sinusitis or sinus infections. However, there are vaccines against viruses and bacteria that may cause some infectious sinusitis. Vaccination against pathogens known to cause infectious sinusitis may indirectly reduce or prevent the chance of getting the disease however, no specific studies support this assumption. Fungal vaccines against sinusitis are not available, currently.
If you are prone to recurrent bouts of a “yearly sinus infection” it may be important to consider allergy testing to see if this is the underlying cause of the recurring problem. Treatment of the allergy may prevent secondary bacterial sinus infections. In addition, sinus infections may be due to other problems such as nasal polyps, tumors, or diseases that obstruct normal mucus flow. Treatment of these underlying causes may prevent recurrent sinus infections.
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Which Antibiotics For Sinus Infection Are Most Effective
A leading study reflected various efficacies for each antibiotic commonly prescribed:
90%+ of Amoxicillin, Moxifloxacin & Levofloxacin treatments are effective
70%-80% of Doxycycline, Azithromycin, Erythromycin, Clarithromycin & Cefprozil treatments are effective
50-60% of Cefaclor treatments are effective
80%-90% of High-Dose Amoxicillin, Cefpodoxime Proxetil, Cefixime, and Sulfamethoxazole treatments are effective
Case & Commentary: Part 3
The patient’s hospital course was marked by multiorgan failure, septic shock, and spontaneous bowel perforation requiring hemicolectomy. Examination of the bowel showed Aspergillus, leading to a diagnosis of disseminated aspergillosis. Despite aggressive antifungal therapy, the patient ultimately succumbed to overwhelming infection and died.
This patient suffered a tragic outcome likely related to inappropriate prescribing of antibiotics. While the complications and ultimate outcome of this case are exceedingly rare, unfortunately, the problem of inappropriate antibiotic prescribing remains common. Over the past decade, antibiotic prescribing for ARIs has decreased in response to publicity and education regarding antimicrobial resistance. However, prescribing rates for viral infections remain high: in 2002, nearly half of adults with nonspecific ARIs were still prescribed antibiotics. Limited success in reducing overall antibiotic prescribing may be counteracted by a marked increase in prescribing of broad-spectrum antibiotics, the use of which doubled during the 1990s.
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Case & Commentary: Part 1
A healthy 53-year-old woman presented to her primary care physician with upper respiratory symptoms and possible sinusitis. She was prescribed Augmentin . Despite this therapy, her symptoms persisted. She was then prescribed azithromycin.
Upper respiratory tract infection symptoms are among the most common presenting complaints to primary care physicians, with 83.1 million visits occurring in 2002 , of which 3.1 million were ultimately ascribed to acute sinusitis in adults. Sinusitis occurs after or in conjunction with a viral URI. Inflammation of the respiratory epithelium lining the paranasal sinuses leads to obstruction of the sinus ostia and accumulation of mucus within the sinuses. The adjacent nasal mucosa is invariably inflamed as well. This process leads to the typical sinus symptoms of headache, nasal congestion and discharge, and facial pain or pressure, sometimes accompanied by sneezing, toothache, or fever.
Maxillary pain or tenderness in the face or teeth.
Mucopurulent nasal discharge.
Symptoms have lasted for 7 days or more.
Despite these guidelines, overtreatment of acute sinusitis with antibiotics is common. A 2007 study found that antibiotics were prescribed in 82.7% of outpatient visits due to acute sinusitis. Many of these prescriptions are unnecessary, as the vast majority of cases of sinusitis are viral in originespecially when symptoms have lasted for less than 1 week.
Use Of Amoxicillin In Sinus Infection
Amoxicillin is a very common antibiotic to treat a wide range of bacterial infections. Amoxicillin is particularly useful against certain alpha and beta-hemolytic strains of bacteria that infect sinus cavities, ear, and throat.
Amoxicillin should always be taken when your doctor prescribes it to treat your medical conditions. Amoxicillin is available in different combinations and your doctor will decide what combination or dosage is suitable for you.
For example, Amoxicillin is not a good antibiotic if you are allergic to cephalosporin or penicillin group of medicines. In fact, allergic reactions can be very severe and require immediate medical attention.
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Feel Better Sooner Without Antibiotics
Instead of taking antibiotics for sinusitis, Consumer Reports chief medical adviser, Marvin M. Lipman, M.D., recommends that you get plenty of rest, rinse your nose with a saltwater sinus rinse or spray, drink warm fluids, and inhale steam from a hot bath, shower, or kettle. For pain, he says, try an over-the-counter pain reliever such as acetaminophen or ibuprofen .
If needed, your doctor can prescribe a prescription corticosteroid spray, such as fluticasone or triamcinolone. A systematic review published in JAMA in 2015 found that after saline irrigation, the second-best treatment for chronic sinusitis was a topical corticosteroid spray for a few days.
Side Effects Of Doxycycline For Sinus Infection
Generally, there are only some minor side effects after taking Doxycycline for sinus infection. Common side effects that can occur after taking doxycycline are-
- Diarrhea that is watery or bloody
- Irritation in the throat
- Difficulty breathing
- Little to almost no urination
- Lower count of white blood cells
- Iron supplements and laxatives
- Oral birth control pills
People who are in the habit of drinking alcohol are more likely to side effects of Doxycycline tablets, especially stomach upset. Moreover, when medicine is taken with milk or food it can reduce the absorption of medicine by the body.
The medicine also enhances the sensitivity of the skin to sunlight. Hence, when stepping out of the house, make sure you are properly covered and wearing sunglasses and sunscreen.
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Antibiotic Amoxicillin No Better Than Placebo For Most Sinus Infections
If you have a sinus infection, taking a course of amoxicillin, an antibiotic medication, does not help you recover faster or reduce symptoms any more effectively than taking an inactive placebo, according to a new study by Washington University School of Medicine in St. Louis, Missouri, USA, that is published in the 15 February issue of JAMA.
First author Dr Jane M Garbutt is a research associate professor of medicine at the School of Medicine. She told the media that she and her colleagues believe antibiotics are overused in primary care, and referred to efforts by the Centers for Disease Control and Prevention to encourage more judicious use of the drugs.
We hope this study provides scientific evidence that doctors can use with patients to explain that an antibiotic is not likely to help an acute sinus infection, said Garbutt.
Senior author Dr Jay F Piccirillo, professor of otolaryngology at the School, said:
Our results show that antibiotics arent necessary for a basic sinus infection most people get better on their own.
Sinusitis means inflammation of a sinus, one of the small, air-filled spaces inside the forehead and cheekbones. The sinuses make mucus which normally drains through small tubes into the nose. Most incidences of sinusitis are due to infection and mainly affect the ones in the cheekbones.
Sinusitis is very common in the US, where 1 in 5 prescriptions for antibiotics are for treating the condition.
Driving Or Operating Heavy Machinery
This medicine can cause extreme drowsiness or dizziness in patients. Immediately after taking Doxycycline Tablet or its substitutes, do not drive or operate any heavy machinery.
In addition to the above precautions, make sure that you let the doctor if you are-
- Allergic to drugs such as clarithromycin, erythromycin
- Having issues in the kidneys, muscles, liver or heart
- Having a low level of potassium or magnesium
- Willing to conceive in the future
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When To Consider Antibiotics For Sinus Infections
AAAAI advises that antibiotics for sinus infections should be considered only if you develop a fever of 102° F or higher, you have severe face pain and tenderness, your symptoms last longer than a week or so, or your symptoms improve and then worsen again.
Some patients with acute sinusitis do need antibiotics, and if they continue with a worsening infection without treatment, they can suffer dramatic complications such as loss of vision, meningitis, or brain abscess, Patel says.
If your doctor says you need an antibiotic, ask for generic amoxicillin/clavulanate, according to guidelines from UpToDate, which provides evidence-based treatment information to healthcare providers. Its usually the best choice and works as well as more expensive brand-name antibiotics.
Avoid taking fluoroquinolones, a group of antibiotics that includes ciprofloxacin and levofloxacin . Although widely used, the antibiotics are inappropriate for treating sinus infections and they pose serious risks.
In 2016, after a safety review, the Food and Drug Administration linked fluoroquinolones to disabling and potentially permanent side effects. The agency advised against using the drugs to treat common illnessesbronchitis, sinus infections, and urinary tract infections.
Amoxicillin 875 Mg Sinus Infection
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Viral Vs Bacterial Sinus Infections
Most sinus infections are caused by viruses that create inflammation in the sinuses, leading to blockage that can make it hard to breathe, nasal secretions, postnasal drip, and other discomfort like facial pain around your eyes, cheeks, nose, or forehead.
Knowing thisand that antibiotics dont work on viral infectionsmost healthcare providers first recommend treatments to relieve the symptoms of a sinus infection while you wait for it to resolve.
These may include:
- Over-the-counter such as pseudoephedrine
- Pain relievers like acetaminophen or ibuprofen to ease discomfort from swelling, fever, or sore throat
In rare cases, viral sinus infections can lead to bacterial growth in the nasal passages.
Theres no way to know for sure if you have a bacterial sinus infection without testing a mucus sample.
But even without a sample, two signs typically indicate a bacterial infection and may prompt your provider to prescribe antibiotics:
- A sinus infection that lasts for more than 10 days
- Symptoms of the infection resolve, then back worse a couple days later
Some people think yellow or green mucus may be a sign of a bacterial sinus infection, but colored mucus can occur with viral infections and does not necessarily mean you have a bacterial infection.
If you do have bacterial sinusitis , it should respond to antibiotics within a few days.