What Are The Side Effects Metronidazole And Miconazole
Metronidazole
Flagyl is a useful antibiotic and is generally well tolerated with appropriate use. The most common and minor side effects include:
- Colon cancer in people with Crohn’s disease
Miconazole
Irritation, burning, rash and itching have been reported by patients using topical or vaginal miconazole.
Spread Doses Evenly Throughout The Day
Doses of metronidazole should be spread evenly throughout the day when multiple doses are prescribed. If people miss a dose, they should take the missed dose as soon as they remember. Its important to not take two doses at the same time. If people have trouble remembering to take their medication, they may need to set a timer as a reminder or use a pillbox for the course of their treatment.
How To Fill The Applicator And Use Metronidazole Vaginal Gel
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Which Treatments Are Effective For Bacterial Vaginosis
Bacterial vaginosis can cause symptoms such as discharge with an unpleasant smell. The clindamycin and metronidazole are both effective treatments for bacterial vaginosis. There has not yet been enough research on the possible benefits of lactic acid treatments.
Bacterial vaginosis is quite common and caused by changes in the vaginal flora that allow the rapid growth of specific types of .
The infection can cause a thin, grayish-white discharge with an unpleasant smell, but it often goes undetected. If it does produce symptoms, can be used as an effective treatment, even during pregnancy. Treatment can help lower the slightly increased risk of miscarriage due to the infection, too.
Enhancing Healthcare Team Outcomes

There should be judicious prescribing of metronidazole by providers only for known indications and high clinical suspicion for needing treatment of anaerobic bacterial infections, protozoal infections, and microaerophilic bacterial infections. Overprescribing may contribute to increasing future antibiotic resistance to the drug, so a pharmacy consult is necessary for the prescriber to ensure directed therapy. The documentation already exists regarding increased resistance to metronidazole in the treatment of C. difficile infections. Also, prescribers, nurses, and pharmacists should routinely educate patients to abstain from alcoholic beverages while taking metronidazole, which will help lead to fewer disulfiram reaction symptoms nursing will play a role in this monitoring and for other potential adverse effects. The patient should also be informed by the health care provider of the possible change in urine color while on this medicine. The team of health professionals, including physicians, physician assistants, nurses, and pharmacists, must work together to provide the best care for these patients when using metronidazole in any formulation.
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Ready To Seek Professional Help
Yeast, bacterial vaginosis, and fungal or bacterial infections can get severe if you do not use the proper medications. Seeing a doctor keeps you away from further damage to you. Fortunately, you actually dont have to wait in line to visit a doctor for your health care.
DrAlexa provides an easy, quick, and private online telemedicine service. We will diagnose your illness and deliver the appropriate prescription to your doorstep. Plus, our services are very affordable.
How To Treat A Vaginal Yeast Infection
Vaginal yeast infections are usually treated with antifungal suppositories. Treatment takes up to one week and in most cases its effective. The most common medications for vaginal yeast infection are Monistat and Clotrimazole.
Sometimes yeast infections are difficult to treat and they become chronic. In that case, one of the most potent but at the same time completely natural remedies is boric acid suppositories. Boric acid has been shown to successfully treat persistent and recurrent yeast infections providing lasting results.
One of the best products of this type on the market is BoriCap, they offer same day shipment making it easier for you to start your treatment as soon as possible.
Antibiotics are one of the main causes of yeast infections in women. Metronidazole has been scientifically shown to trigger yeast infections.
Thats why, when youre taking Flagyl remember to supplement your diet with probiotic supplements and probiotic-rich foods.
You can also use probiotic suppositories to further boost your immunity and cut your risk of developing an infection.
If youre already suffering from a yeast infection triggered by antibiotics check my article about different vaginal yeast infection treatment options, or if you prefer, visit my page about natural home remedies for vaginal yeast infection.
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Can An Infection From Yeast Turn Into Bv
As opposed to BV, a vaginal candidiasis is caused by a fungus called candida. Symptoms of BV and an infection from yeast both usually include vaginal discharge. BV typically causes discharge thats thin and gray or yellow. A yeast infection causes discharge that is thick and white, with a cottage-cheese type appearance.
How Does It Work
Metronidazole works by destroying and preventing the creation of DNA in the infecting organisms. Unlike most other drugs, metronidazole is able to treat central nervous system infections by penetrating the blood-brain barrier.
In order to thrive, your dogs body parts need good circulation and oxygen. Tissue that is damaged usually has poor oxygen circulation. In these areas, only certain pathogens that do not require oxygen can thrive. Metronidazole inhibits repair enzymes in the cells that exist in these unoxygenated environments, resulting in the death of bacterial cells.
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Can I Take Metronidazole If Im Pregnant Or Breastfeeding
May harm an unborn baby. Do not use metronidazole to treat trichomoniasis during the first trimester of pregnancy. Tell your doctor if you become pregnant.
You should not breastfeed within 24 hours after using metronidazole. If you use a breast pump during this time, throw out the milk and do not feed it to your baby.
What Are The Side Effects Of Metronidazole
Metronidazole vaginal gel side effects might occur when medication does more than treating the intended problem. The most common vaginal metronidazole side effects differ depending on the patients overall health, condition stage, age, weight, and gender. They may range from minor to severe.
Below is a list of side effects of using Vaginal Metronidazole:
You must consult your doctor if you experience these symptoms while using Metronidazole vaginal gel.
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How To Use Metronidazole Vaginal Gel
- Before you start the treatment, read the manufacturer’s printed information leaflet from inside the pack. The manufacturer’s leaflet will give you more information about metronidazole, and it will also explain how to use the gel and applicator.
- If you forget to use the gel, use it as soon as you remember. If you do not remember until the following day, use the gel as normal on your next dose . Use the gel for the correct number of days in total.
What Are The Possible Side Effects Of Metronidazole

Get emergency medical help if you have signs of an allergic reaction or a severe skin reaction .
- new or worsening symptoms of infection
- painful or difficult urination
- a light-headed feeling
- vaginal itching or discharge or
- blisters or ulcers in your mouth, red or swollen gums, trouble swallowing.
Stop taking the medicine and call your doctor right away if you have neurologic side effects :
- numbness, tingling, or burning pain in your hands or feet
- vision problems, pain behind your eyes, seeing flashes of light
- muscle weakness, problems with speech or coordination
- trouble speaking or understanding what is said to you
- fever, neck stiffness, and increased sensitivity to light.
Metronidazole can cause life-threatening liver problems in people with Cockayne syndrome. If you have this condition, stop taking metronidazole and contact your doctor if you have signs of liver failure –nausea, stomach pain , dark urine, clay-colored stools, or jaundice .
Side effects may be more likely in older adults.
Common side effects may include:
- depression, trouble sleeping, feeling irritable
- headache, dizziness, weakness
- nausea, vomiting, loss of appetite, stomach pain
- diarrhea, constipation
- vaginal itching or discharge, pain during sex
- mouth sores or
- swollen, red, or “hairy” tongue.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Availability In Various Forms
Metronidazole tablets are available in various preparations such as 250 mg, 500 mg, 750 mg. Apart from these, 375 mg capsules are also available. Cream and gel have 0.75% and 1% metronidazole, while the lotion contains 0.75%. Injections with 5 mg/ml of metronidazole are sometimes used. Cream or gel containing this antibiotic is used to treat acne rosacea. The vaginal gel is used to treat bacterial vaginosis. For giardia, 250 mg tablets are recommended, three times daily, for 5 days. The following table explains the uses of metronidazole more clearly.
Name of the Disease | |
750 mg orally, daily 3 times for 5 10 days | |
Amoebic liver abscess | 500 750 mg orally, daily 3 times for 5 10 days |
Anaerobic infections | 7.5 mg/kg orally, every 6 hours, not to exceed 4 grams daily |
Bacterial Vaginosis | 750 mg orally, once daily for 7 days |
Bacterial Vaginosis | 0.75% vaginal gel, apply it once or twice daily for 5 days |
Clostridium difficile infection | 250 500 mg orally, daily 4 times for 5 10 days / 500 750 orally, daily 3 times for 5-10 days |
Giardia infection | 250 mg orally, daily 3 times for 5 days |
Helicobacter pylori infection | 800 1500 mg orally, daily for several days in combination with other drugs |
Pelvic inflammatory disease | 500 mg orally, daily twice for 14 days in combination with other drugs |
Trichomoniasis | 2g single dose or 1 g twice, for one day |
Rosacea | gel 0.75 1%, apply topically, once daily |
What May Interact With This Medication
Do not take this medication with any of the following:
This medication may also interact with the following:
This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.
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How Should I Use This Medication
Talk to your care team about the use of this medication in children. While this medication maybe prescribed for children as young as 12 years for selected conditions, precautions do apply.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
Important Information About All Medicines
Never use more than the prescribed dose. If you suspect that you or someone else might have swallowed some of this gel by accident, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty. This medicine is for you. Never give it to other people even if their condition appears to be the same as yours. If you buy any medicines, check with a pharmacist that they are suitable to take with your other medicines. If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are using. Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you. If you have any questions about this medicine, ask your pharmacist. |
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How Long Does It Take For Metronidazole To Escape Your System
Most courses of metronidazole last for about 7 days, however, many may be as short as 3 days and some so long as 14 days. For certain infections you may well be given an individual, larger dose of metronidazole, usually five 400 mg tablets to use simultaneously. Take each of your doses with a snack or perhaps after eating a meal.
What Should I Know About Storage And Disposal Of This Medication
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture . Do not freeze or refrigerate it.
It is important to keep all medication out of sight and reach of children as many containers are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location â one that is up and away and out of their sight and reach.
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community. See the FDA’s Safe Disposal of Medicines website for more information if you do not have access to a take-back program.
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How To Take Metronidazole
Use Metronidazole exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Metronidazole oral is taken by mouth.
Metronidazole injection is given as an infusion into a vein. A healthcare provider will give you this injection if you are unable to take the medicine by mouth.
Shake the oral suspension . Measure a dose with the supplied measuring device .
Swallow the extended-release tablet whole and do not crush, chew, or break it.
If you are treating a vaginal infection, your sexual partner may also need to take metronidazole so you don’t become reinfected.
Metronidazole is usually given for up to 10 days in a row. You may need to repeat this dosage several weeks later.
Keep using this medicine even if your symptoms quickly improve. Skipping doses could make your infection resistant to medication. Metronidazole will not treat a viral infection .
Metronidazole will not treat a vaginal yeast infection. You may even develop a new vaginal yeast infection, which may need to be treated with antifungal medication. Tell your doctor if you have symptoms such as itching or discharge during or after treatment with metronidazole.
Do not share this medicine with another person, even if they have the same symptoms you have.
What Are The Possible Side Effects Of Metronidazole Vaginal

Get emergency medical help if you have signs of an allergic reaction or a severe skin reaction .
Rare but serious side effects may include:
- numbness, burning, pain, or tingly feeling in your hands or feet.
Common side effects may include:
- vaginal itching or discharge
- stomach pain, nausea, diarrhea or
- cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Metronidazole Topical Side Effects
Get emergency medical help if you have signs of an allergic reaction:hives difficulty breathing swelling of your face, lips, tongue, or throat.
Metronidazole topical may cause serious side effects. Call your doctor at once if you have:
-
numbness, tingling, or burning pain in your hands or feet or
-
stinging or burning when you apply metronidazole topical.
Common side effects of metronidazole topical may include:
-
burning or stinging
What Are The Dosages Of Metronidazole
Dosage of Metronidazole:
Adult and Pediatric Dosage Forms and Strengths
Capsule
Anaerobic Bacterial Infections
- Loading dose: 15 mg/kg intravenously not to exceed 4 g/day
- Maintenance dose: 7.5 mg/kg oral/intravenous every 6 hours x 7-10 days
- Prevention following sexual assault
- 2 g orally as a single dose 3-drug regimen that also includes ceftriaxone or cefixime, PLUS azithromycin or doxycycline
Bacterial Vaginosis
- 500 mg orally twice daily x 7 days, OR
- 2 g orally once/day single dose, OR
- Extended-release: 750 mg orally once/day x 7 days
- Prophylaxis start after mechanical bowel preparation the afternoon and evening before surgery
- 1 g orally every 6-8 hours for 3 doses
- 15 mg/kg IV over 30-60 min complete approximately 1 hour before surgery may administer 7.5 mg/kg IV over 30-60 min at 6 and 12 hours after initial dose for maintenance discontinue within 12 hours after surgery
- Adult: 250 mg orally every 8 hours for 7 days alternatively, 375 mg orally every 12 hours for 7 days
- 2 g orally once daily single dose alternatively, 1g orally every 12 hours for 2 doses
- Pediatric: less than 45 kg body weight: 15 mg/kg/day IV/oral divided every 8 hours for 7 days not to exceed 2 g/day
- Adult: 500-750 mg orally every 8 hours for 5-10 days
- Pediatric: 35-50 mg/kg orally divided once every 8 hours for 10 days
Gardnerella Infection
Helicobacter Pylori Infection
Pouchitis
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